About the software
The trajalign module distribution is designed to align in space and in time the trajectories of diffraction limited objects, which are imaged in living cells with fluorescence microscopy.
The original version of the software was developed in R and is no longer mantained. The software in its original version was used to visualise the dynamic architecture of the endocytic machineries in yeast cells (Picco, et al., eLife 2015) and to resolve subtle phenotypes induced by genetic mutations in the yeast cell (Kukulski, Picco, et al., eLife 2016). If interested, the R version of the code can be downloaded from Picco, et al., 2015 at the following link (deprecated).
The new version of the software published here is rewritten in Python. The software is more efficient, it is easier to use, and its code is much clearer than in its original R version.
The software was developped and is currently mantained by Andrea Picco in the Kaksonen laboratory.
Licence
All the software here is distributed under the terms of the GNU General Public License Version 3, June 2007. trajalign is a free software and comes with ABSOLUTELY NO WARRANTY. You are welcome to redistribute the software. However, we deeply appreciate if the use of our software would result in citations of
where we detail our imaging and tracking method.
Thank you and enjoy trajalign!
About the author
I am a physicist who has always been fascinated by biology and its complexity. I believe that the careful design of quantitative microscopy experiments and a rigorous data analysis can allow scientists to visualise and understand the molecular details of biological processes, directly in living cells. Currently, I am a Mâitre assistant in the group of Professor Kaksonen.
Some external links: